PHA 6443 Case Studies in Clinical Pharmacogenomics


This course will provide an overview of the use of pharmacogenomic data to inform clinical and therapeutic decision making for gene-drug pairs across a range of conditions.

  • Credit(s): 3
  • Course Format: Asynchronous
  • Required: This is an elective course.
    • (GMS 6224) Foundations in Precision Medicine: Medical Molecular Genetics
    • (PHA 6134) Foundations in Precision Medicine: Genomic Technologies
    • (PHA 6935) Foundations in Precision Medicine: Genetic Epidemiology
    • (PHA 6120) Principles of Pharmacogenomics

Course Objectives

Upon completion of this course, the student will be able to:

  • Describe the role of pharmacogenomics in the patient care process
  • Identify drugs whose clinical outcomes are affected by genetic variability
  • Interpret and apply evidence for clinical utility of genotype-informed drug therapy
  • Demonstrate evidence-based clinical decision making that incorporates clinical and genetic factors for patient case scenarios across a spectrum of diseases
  • Communicate rationale for drug therapy changes informed by genotype
  • Assess the effectiveness of genotype-informed drug therapy on the basis of clinical and laboratory parameters
  • Identify the key components and steps required for the successful implementation of pharmacogenomics in clinical practice.