Overview
Genetic epidemiology utilizes specialized molecular and statistical methods to identify genetic factors associated with phenotypes that may be causally related to human disease. This course provides an exposure to fundamental concepts, terminologies and principles in human population genetics and applied biostatistical techniques relevant to design, conduct and interpretation of genetic epidemiologic studies. This is a 5-week, 1-credit online graduate-level course.
- Credit(s): 1
- Course Format: Asynchronous
- Required: Yes
- Prerequisites:
- (GMS 6224) Foundations in Precision Medicine: Medical Molecular Genetics
- (PHA 6134) Foundations in Precision Medicine: Genomic Technologies
Course Objectives
- Describe basic concepts and terminologies in human population genetics
- Explain fundamental principles and theories in genetic epidemiology
- Review design and interpretation of studies of familial aggregation of disease
- Describe various genetic markers commonly used in genetic epidemiology studies
- Explain the difference between genetic linkage and association analyses
- Interpret results of studies using candidate gene approaches results of studies of genome-wide
- Interpret (agnostic) approaches
- Understand the types of bias that could occur in genetic epidemiology studies
- Critically review articles in the area of genetic epidemiology
- Describe the application of genetic epidemiology, study results to other fields of research and healthcare