Overview
This 5-week, 1-credit online graduate-level survey course will cover a range of topics in human genetics, focusing on mutation/variant pathogenic mechanisms and applications in the context of human disease. This course will review concepts and provide a foundation for understanding mechanisms of human molecular pathogenesis at the gene and chromosome level, and understanding the application of genetic knowledge in modern healthcare using real-world examples.
- Credit(s): 1
- Course Format: Asynchronous
- Required: Yes
Course Objectives
Develop a greater understanding of the function and role of the human genome in disease, specifically:
- The human karyotype, modes of Mendelian inheritance, and factors affecting interpretation thereof.
- Mechanisms by which genetic variations contribute to human phenotypes and applications in the clinic.
- Molecular pathogenetic mechanisms of, and techniques to identify, high-penetrance mutations.
- Pathogenesis at the RNA level.
- Genetic association of multifactorial traits, and functional effects of alleles.
- Epigenetics in hereditary disease and genetic susceptibility.
- Cancer genetics concepts: somatic mutations and mechanisms.
*Please note that this syllabus is subject to change. Use the updated syllabus in Canvas as the official course syllabus.
Library Access
UF online graduate students enjoy the same library privileges as on-campus students. Visit the University of Florida Libraries to find books, journals and more.